Neuroscience of Alcohol

Mechanisms and Treatment
Herausgeber: Preedy, Victor R

• Broschiertes Buch

Produktbeschreibung

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world's most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance.

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Produktdetails

• Verlag: Elsevier Science Publishing Co Inc
• Seitenzahl: 736
• Erscheinungstermin: 19. März 2019
• Englisch
• Abmessung: 279mm x 218mm x 37mm
• Gewicht: 1940g
• ISBN-13: 9780128131251
• ISBN-10: 012813125X
• Artikelnr.: 53607171

Inhaltsangabe

PART I: INTRODUCTORY CHAPTERS 1. Becoming a "Successful" Drinker and a
Graduate: A Sociological Perspective on Alcohol Consumption by University
Students 2. Molecular Genetics Meets Sociology: Birth Cohort Effects on
Alcohol Use and Relationship With Candidate Genes 3. Alcohol and Women:
Unique Risks, Effects, and Implications for Clinical Practice 4. ADH and
ALDH Polymorphisms in Alcoholism and Alcohol Misuse/Dependence 5.
Acetaldehyde in the Brain After Ethanol Exposure: Research Progress and
Challenges 6. Consequences of Ethanol Exposure on Neurodevelopment 7.
Animal Models of Binge Drinking: Behavior and Clinical Relevance
PART II: NEUROBIOLOGY 8. Prenatal Alcohol Exposure: Developmental
Abnormalities in the Brain 9. Connecting Prenatal Alcohol, Its Metabolite
Acetaldehyde, and the Fetal Brain 10. Fetal Alcohol Exposure and the
Central Nervous Control of Breathing 11. Synaptic Plasticity in the
Hippocampus and Alcohol Exposure During Brain Development 12. Ethanol and
Cortical Spreading Depression: The Protective Role of ¿-Tocopherol 13.
Brain Electrophysiological Signatures in Human Alcoholism and Risk 14.
Alcohol and Hippocampal Epileptiform Activity 15. Effects of Alcohol on the
Corpus Callosum 16. The Role of the Lateral Habenula Circuitries in Alcohol
Use Disorders 17. Ventral Pallidum and Alcohol Addiction 18. The
Hyperpolarization-Activated Cyclic Nucleotide-Gated Ion Channels in the
Rewarding Effects of Ethanol 19. Neuroimmune Aspects of Alcoholism and
Affective Comorbidity 20. Social Drinking and Motor Inhibition:
Evidences From FMRI Go/Nogo Tasks fMRI Studies on Alcohol Effect on
Inhibition 21. Myelopathy and Neuropathy Associated With Alcoholism 22.
Alcohol Consumption and the Risk of Amyotrophic Lateral Sclerosis 23.
Alcohol and Pain Interactions 24. Neurobiological Aspects of
Ethanol-Derived Salsolinol 25. Brain Networks in Active Alcoholism and
Enduring Recovery: Functional Magnetic Resonance Imaging,
Electrophysiological Studies, and Implications for Targeted Treatments 26.
Central Role of Amygdala and Hypothalamus Neural Circuits in Alcohol
Withdrawal Symptom
PART III: PSYCHOLOGY, BEHAVIOR, AND ADDICTION 27. Neural Reward Processing
in Human Alcoholism and Risk: A Focus on Event-Related Potentials,
Oscillations, and Neuroimaging 28. Occipito-Temporal Sensitivity and
Emotional Faces in Alcohol Use Disorder 29. Alcohol and Violence in
Psychopathy and Antisocial Personality Disorder: Neural Mechanisms 30.
Language Lateralization in Fetal Alcohol Spectrum Disorders 31. Deprivation
in Rewards and Alcohol Misuse 32. Alcohol (Mis)Use in Individuals With Mild
to Borderline Intellectual Disability 33. Sex, Stress, and Neuropeptides
Interact to Influence Alcohol Consumption 34. Maternal Separation Stress in
Fetal Alcohol Spectrum Disorders: A Case of Double Whammy 35. Impulsivity
and Binge Drinking: A Neurocognitive Perspective 36. Acetaldehyde and
Motivation 37. Age-Related Differences in the Appetitive and Aversive
Motivational Effects of Alcohol 38. Alcoholism in Bipolar Disorders: An
Overview of Epidemiology, Common Pathogenetic Pathways, Course of Disease,
and Implications for Treatment 39. Socio-Emotional Deficits in Severe
Alcohol Use Disorders 40. Relapse Risks in Patients With Alcohol Use
Disorders 41. The Neurocognitive Effects of Alcohol Hangover: Patterns of
Impairment/Nonimpairment Within the Neurocognitive Domains of the
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition
PART IV: PHARMACOLOGY, NEUROACTIVES, MOLECULAR, AND CELLULAR BIOLOGY 42.
Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity
and Alcohol Use Disorders Risk 43. Alcohol's Effects on Extracellular
Striatal Dopamine 44. Nicotinic Cholinergic Mechanisms in Alcohol Abuse and
Dependence 45. Opioid System and Alcohol Consumption 46. The
Enkephalinergic System and Ethanol Effects 47. Alcohol and Central
Glutamate Activity: What Goes Up Must Come Down? 48. Ethanol and
Hippocampal Gene Expression: Linking in Ethanol Metabolism,
Neurodegeneration, and Resistance to Oxidative Stress 49. Stress, Alcohol,
and Hippocampal Genes 50. Genes and Alcoholism: Taste, Addiction, and
Metabolism 51. Ethanol Exposure During Development, and Brain Oxidative
Stress 52. Alcohol-Induced Oxidative Stress in the Brain: Suggested
Mechanisms, Associated Disorders, and Therapeutic Strategies 53. Lead
Exposure and Ethanol Intake: Oxidative Stress as a Converging Mechanism of
Action
PART V: ALCOHOL AND OTHER ADDICTIONS 54. Alcohol and Gambling Addiction 55.
Neuroscience of Alcohol and Crack Cocaine Use: Metabolism, Effects and
Symptomatology 56. The Impact of Ethanol Plus Caffeine Exposure on
Cognitive, Emotional, and Motivational Effects Related to Social
Functioning
PART VI: BIOMARKERS AND SCREENING 57. Biomarkers of Alcohol Misuse 58.
Phosphatidylethanol Homologs in Blood as Biomarkers for the Time Frame and
Amount of Recent Alcohol Consumption 59. Metabolomics to Differentiate
Alcohol Use Disorders From Social Drinkers and Alcohol-Naive Subjects 60.
Meconium Biomarkers of Prenatal Alcohol Exposure 61. Applications of the
Alcohol Use Disorders Identification Test (AUDIT) in Distinct Health Areas
62. Craving Measurement and Application of the Alcohol Craving Experience
Questionnaire
PART VII: TREATMENTS, STRATEGIES AND RESOURCES 63. Negative Emotions and
Alcohol Use Disorder Treatment 64. Use of Baclofen in Alcohol Use Disorder:
A Clinical Approach 65. Baclofen-Induced Neurotoxicity 66. Treatment With
Nalmefene in Alcoholism 67. Dual Therapy for Alcohol Use Disorders:
Combining Naltrexone With Other Medications 68. The Avermectin Family as
Potential Therapeutic Compounds for Alcohol Use Disorder: Implications for
Using P2X4 Receptor as a Drug-Screening Platform 69. Alcohol Withdrawal
Syndrome: Clinical Picture and Therapeutic Options 70. Resources for the
Neuroscience of Alcohol