This book presents an overview of the recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections. In addition, neutrophils represent a unique model for studying fundamental questions of cellular biochemistry and molecular biology. This monograph provides a detailed description of signal transduction, generation of reactive oxygen, mechanisms of migration and death of these cells.Besides that, it contains unique information about its role in periodontal disease.Finally, this monograph describes recent advances in attempts to improve neutrophil function.