Andere Kunden interessierten sich auch für
![SINGLE-PARTICLE CRYO-ELECTRON MICROSCOPY]( "SINGLE-PARTICLE CRYO-ELECTRON MICROSCOPY")
SINGLE-PARTICLE CRYO-ELECTRON MICROSCOPY226,99 €![Advances in Biomedical Image Processing and Analysis]( "Advances in Biomedical Image Processing and Analysis")
Advances in Biomedical Image Processing and Analysis77,99 €![Particle swarm optimizer: Economic dispatch with valve point effect using various PSO techniques]( "Particle swarm optimizer: Economic dispatch with valve point effect using various PSO techniques")
Particle swarm optimizer: Economic dispatch with valve point effect using various PSO techniques34,99 €![Gross and Microscopic Anatomy on Small Intestine of the Kadaknath Fowl]( "Gross and Microscopic Anatomy on Small Intestine of the Kadaknath Fowl")
Gross and Microscopic Anatomy on Small Intestine of the Kadaknath Fowl46,99 €![Lip Image Biometric]( "Lip Image Biometric")
Lip Image Biometric23,99 €![Particle Dispersion and Deposition in Multiphase Turbulence Flow]( "Particle Dispersion and Deposition in Multiphase Turbulence Flow")
Particle Dispersion and Deposition in Multiphase Turbulence Flow44,99 €![A multi-omics view on the pathogen Yersinia pseudotuberculosis ¿ bridging metabolism and virulence]( "A multi-omics view on the pathogen Yersinia pseudotuberculosis ¿ bridging metabolism and virulence")
A multi-omics view on the pathogen Yersinia pseudotuberculosis ¿ bridging metabolism and virulence29,15 €
In this thesis four approaches to increase the quality and assure the validity of three-dimensional (3D) models generated within the single particle cryo-electron microscopy (CryoEM) workflow are introduced. ProteoPlex is a high-throughput technique and software tool for the evaluation of the most stabilizing biochemical conditions of macromolecular complexes. The validation technique 3D correlation of tilted pairs (3DCTP) can be applied alongside the single particle refinement cycle to detect model bias utilizing tilted pair images. A new analysis method identifies the presence of overfitting in high resolution CryoEM 3D structures. Finally, a set of criteria covering different model quality aspects of the generated 3D structure is introduced.