New Cytokines as Potential Drugs

Herausgegeben:Narula, Satwant K.; Coffman, Robert

• Broschiertes Buch

Produktbeschreibung

Over the past ten years, a number of cytokines and growth factors haveproven to be as effective therapeutics. While these products havecertainly established recombinant biologics as a major pharmaceuticalgrowth sector, the continued interest in this class of drugs arises fromthe fact that today we have a far better understanding of the humanimmune response, both at a cellular and molecular level.This has resulted in a more methodical characterisation of these factorswhich has given clinical researchers an opportunity to plan Phase 1clinical trials that can provide substantial information on the activityof the cytokine in humans. Currently, a great deal of effort is alsobeing channelled into identifying cytokines from the various DNAdatabases.Our major objective for this book is to profile cytokines that have beenrecently identified. The therapeutic potential of these cytokines basedon their known properties will be discussed by the authors. The main aimof this book is to provide..

Produktdetails

• Progress in Inflammation Research
• Verlag: Birkhäuser / Birkhäuser Basel / Springer, Basel
• Artikelnr. des Verlages: 978-3-0348-9575-0
• Softcover reprint of the original 1st ed. 2000
• Seitenzahl: 156
• Erscheinungstermin: 23. Oktober 2012
• Englisch
• Abmessung: 235mm x 155mm x 9mm
• Gewicht: 248g
• ISBN-13: 9783034895750
• ISBN-10: 3034895755
• Artikelnr.: 39173540

Autorenporträt

Our major objective for this book is to profile cytokines that have been
recently identified. The therapeutic potential of these cytokines based
on their known properties will be discussed by the authors. The main aim
of this book is to provide both academic and industry researchers with
the current status of research with each of these cytokines and the
development status of those that are already in clinical...

Inhaltsangabe

Contents. List of Contributors. Cuss, F. M.: Interleukin 5. Narula, S., Smith, S. and Grint, P.: Interleukin 10. Cruikshank, W. W., Cornfeld, H. and Center, D. M.: Interleukin 16. Fossiez, F., Nicolas, J.-F. and Lebecque, S.: Interleukin 17. Kurimoto, M.: Interleukin 18. McKenna, H. J.: FLT3 Ligand. Jimenez, P. A., Greenwalt, D., Mendrick, D. L., Rampy, M. A., Su, J., Leung, K. H. and Connolly, K. M.: Keratinocyte Growth Factor. Lira, S. A., Zavodny, P. J. and Lundell, D.: Chemokines. Index