Nitric oxide and post-traumatic stress disorder - Oosthuizen, Frasia
38,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 6-10 Tagen
  • Broschiertes Buch

Stress-restress evokes a complex neurobiological response in the hippocampus involving neuro-excitatory and neurotoxic pathways, as well as neuroinhibitory and neuroprotective responses to chronic stress.One of these changes involves a long-lasting increase in hippocampal iNOS activity that is accompanied by a reactive downregulation of hippocampal NMDA receptors and dysregulation of inhibitory GABA pathways. These perturbations may have importance in explaining the increasing evidence for stress-related hippocampal degenerative pathology and cognitive deficits seen in patients with PTSD.…mehr

Andere Kunden interessierten sich auch für
Produktbeschreibung
Stress-restress evokes a complex neurobiological response in the hippocampus involving neuro-excitatory and neurotoxic pathways, as well as neuroinhibitory and neuroprotective responses to chronic stress.One of these changes involves a long-lasting increase in hippocampal iNOS activity that is accompanied by a reactive downregulation of hippocampal NMDA receptors and dysregulation of inhibitory GABA pathways. These perturbations may have importance in explaining the increasing evidence for stress-related hippocampal degenerative pathology and cognitive deficits seen in patients with PTSD. Nitric oxide thus plays a major role in the pathophysiology of PTSD, thus presenting an area of major therapeutic opportunity for this mental illness.
Autorenporträt
Frasia Oosthuizen completed a BPharm, MSc and PhD (Pharmacology) at the Pothefstroom University for CHE (now North-West University). Her postgraduate research focused on mental illness. She is a senior lecturer in Pharmacology at the University of KwaZulu-Natal. Her main areas of research are Psychopharmacology, as well as Pharmacy Education