Non-coding RNAs and Cancer

Herausgegeben:Fabbri, Muller

• Gebundenes Buch

Produktbeschreibung

This book provides essential information of the biogenesis, physiology and de-regulation of non-coding RNAs in cancer. It guides the reader to the most widely and effectively used bioinformatic approaches to the study of miRNAs.

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This book will comprehensively cover the most updated knowledge on the role of non-coding RNAs in human cancer. The Reader will be guided from the definition of what non-coding RNAs are to the translational and therapeutic implications of these fascinating molecules for cancer patients, through some of the most important discoveries clarifying the role of non-coding RNAs in human carcinogenesis. Although most of the current discoveries involve microRNAs (miRNAs), other non-coding RNA, with a proven involvement in human cancer, will be covered by this book, which will therefore represent the first, extensive publication on the whole category of non-coding RNAs in human cancer.

Produktdetails

• Verlag: Springer / Springer New York / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4614-8443-1
• 2014
• Seitenzahl: 292
• Erscheinungstermin: 29. Oktober 2013
• Englisch
• Abmessung: 241mm x 160mm x 20mm
• Gewicht: 549g
• ISBN-13: 9781461484431
• ISBN-10: 146148443X
• Artikelnr.: 38547686

Inhaltsangabe

Introduction.- Biogenesis and Physiology of microRNAs.-Detecting non-coding RNA expression: from arrays to next generation sequencing.- MicroRNAs in Solid Tumors.-MicroRNAs in hematologic malignancies.- miRNAs as Cancer Biomarkers.- Unraveling the complex network of interactions between non-coding RNAs and epigenetics in cancer.- MicroRNA SNPs in Cancer.- Bioinformatics Approaches to the study of microRNAs.- Beyond miRNAs: role of other non-coding RNAs in cancer.- Translational Implications for non-coding RNA in Cancer.- Index.