Non effervescent tablets of cefuroxime axetil - Venkata Ratnamala, Kolapalli; Anisha, Yelisetti
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Oral drug delivery systems continue to be the most popular route of administration due to its versatility, ease of administration and patient compliance. A number of oral controlled release systems have been developed to improve the delivery of drugs to the systemic circulation. Rapid gastro intestinal transit will prevent complete drug release leading to diminished activity. Gastro retentive drug deliveries are designed to prolong and delay the gastric emptying time (GET). GET, the most important asset which helps the dosage form to reside in the stomach for longer time than convectional…mehr

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Produktbeschreibung
Oral drug delivery systems continue to be the most popular route of administration due to its versatility, ease of administration and patient compliance. A number of oral controlled release systems have been developed to improve the delivery of drugs to the systemic circulation. Rapid gastro intestinal transit will prevent complete drug release leading to diminished activity. Gastro retentive drug deliveries are designed to prolong and delay the gastric emptying time (GET). GET, the most important asset which helps the dosage form to reside in the stomach for longer time than convectional dosage form. Retention of oral dosage form in the upper gastrointestinal tract (GIT) causes prolonged contact time of drug with GI mucosa, leading to higher bioavailability. Drugs which are having shorter half lives, the drugs which are eliminated quickly, and the drugs which are incompletely absorbed from the small intestine are the suitable drug candidates for formulating them into gastro retentive systems.
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Autorenporträt
K.V. Ratnamala completed B.Pharm, M. Pharm and Ph.D from university college of pharmaceutical sciences, Andhra university, Visakhapatnam. Currently working as Assistant professor I. RBVRR women's college of pharmacy, Hyderabad from past 7 years. Field of interest includes gastric floating drug delivery. Guided around 11 M. Pharmacy students.