NON-WILMS PEDIATRIC RENAL TUMORS - Sahraoui, Ghada
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Non-Wilms pediatric renal tumors are rare and pose diagnostic problems because of clinical, histological and molecular heterogeneity. The diagnostic challenge consists in their morphological similarities and the absence of an immunohistochemical marker specific for each histological type. The objective of our study was to determine their anatomopathological characteristics.Our study was retrospective and included 16 cases collected in the department of anatomy and pathological cytology of the Salah Azaiez Institute of Tunis over a period of 19 years from 2000 to 2019.Our results included 9…mehr

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Produktbeschreibung
Non-Wilms pediatric renal tumors are rare and pose diagnostic problems because of clinical, histological and molecular heterogeneity. The diagnostic challenge consists in their morphological similarities and the absence of an immunohistochemical marker specific for each histological type. The objective of our study was to determine their anatomopathological characteristics.Our study was retrospective and included 16 cases collected in the department of anatomy and pathological cytology of the Salah Azaiez Institute of Tunis over a period of 19 years from 2000 to 2019.Our results included 9 cases of clear cell renal sarcoma, 4 cases of rhabdoid tumor, 2 cases of renal cell carcinoma with Xp 11.2 translocation and one case of Ewing's sarcoma (ES). Immunohistochemistry showed Vimentin positivity only in all SRCC cases, epithelial markers (EMA, CK) positivity in TR, constant TFE3 positivity in tCR and CD99 positivity in SE.Our results are in agreement with the literature. The histological diagnosis is still not obvious, hence the almost constant use of immunohistochemistry.
Autorenporträt
Abitur im Jahr 2005Facharztdiplom in pathologischer Anatomie und Zytologie im Jahr 2017Abschluss der Assistenzzeit im Jahr 2017