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IgA glomerulonephritis (IgAGN) is one of the most common forms of primary glomerulonephritis worldwide, accounting for 25 50 % of all patients with primary glomerulopathy. The hallmark for diagnosis is the deposition of immunoglobulin A (IgA) in the glomerular mesangium, leading to histological damage of various degrees. A broad spectrum of clinical presentation and variable prognosis is typical for the disease and approximately 25 30 % of patients eventually develop end-stage renaldisease (ESRD).After the description of the disease in the late 1960s a considerable body of information has…mehr

Produktbeschreibung
IgA glomerulonephritis (IgAGN) is one of the most common forms of primary glomerulonephritis worldwide, accounting for 25 50 % of all patients with primary glomerulopathy. The hallmark for diagnosis is the deposition of immunoglobulin A (IgA) in the glomerular mesangium, leading to histological damage of various degrees. A broad spectrum of clinical presentation and variable prognosis is typical for the disease and approximately 25 30 % of patients eventually develop end-stage renaldisease (ESRD).After the description of the disease in the late 1960s a considerable body of information has accumulated especially on the prognostic features and etiology of IgAGN. The purpose of the present series was to further investigate the prognostic role of insulin resistance, inflammatory markers and alcohol consumption and to gather data on the use of the biomarkers available in evaluating alcohol consumption in patients with IgAGN.
Autorenporträt
Kati Kaartinen graduated from Medical School of Kuopio University, Finland in 1996 and is a specialist in Internal medicine and Nephrology. Her special interest is IgA glomerulonephritis and she has been working as a nephrologist in the University Hospital of Helsinki since 2006.