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Pyrazoles represent one of the most active classes of compounds possessing wide Spectrum of biological activities. Microwave irradiation as an unconventional energy source offers reduced chemical reaction times, reduced side reactions, increased yield and improved reproducibility. Multi-component reactions under microwave irradiation often create complete and complex molecular products in a single synthetic step. The present work has been a continuation of our work from the series of four books comprising of synthesis and QSAR study of Pyrimidine derivatives, Pyrimidines fused with heterocyclic rings, Quinazolines and Novel Pyrazole derivatives: Part I. The Present book entitled as "Novel Pyrazole derivatives: Part II: Synthesis and Biological Prediction Study" comprises of Chapters 1 to 5 which describe in detail the synthesis, characterization and biological prediction study of bipyrazolyl derivatives, pyrazolyl thiazines, pyrazol-1-yl-thiazolidin-4-one, pyrazolyl amino pyrazoles, pyrazolo pyrazoles respectively. The content in the books is highly significant for the researchers and students of synthetic organic, heterocyclic, pharmaceutical & medicinal chemistry.