The purpose of the study was to examine the perceptions of nurses regarding ethico-legal training in Ghana. The study further determined whether there were any discrepancies regarding ethico-legal training of nurses in Ghana, using six hospitals in the Upper West Region (Province). Data were collected through a quantitative, cross sectional research design. Out of 150 people constituting the study population, a sample size of 110 respondents was drawn. A self-developed questionnaire was used to collect data. Nurses who have been in practice for at least five years answered the questionnaires. The convenience sampling technique was found to be appropriate for this study. The Statistical Package for the Social Sciences (SPSS) was used to analyse data. The findings revealed that although ethico-legal topics were contained in the nursing training curriculum, majority of nurses did not receive teaching/training on them, making nurses vulnerable to litigation.