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The immune system acts to protect the host from infections agents that exist that exist in the environment (bacteria, viruses, fungi, parasites) and from other noxious insults. The immune system is constantly active. The immune system has two functional divisions (the innate and the acquired). Both components involve various bloods - borne factors (complement, antibodies, cytokines and cells). The immune system components are interrelated and act in highly coordinated and specific manner and must distinguish between self and non-self-materials, so the effectors mechanisms of the immune system are very tightly regulated. Failure of these regulatory mechanisms results in the full might of the immune system being in appropriately directed against body tissues and the development of autoimmune disease.