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Pregnancy is a physiological situation that disturbs the haemostatic balance and therefore constitutes an additional thromboembolic risk in thrombophilic women, incriminated in the occurrence of multiple complications. Thus, our research work aims to explore, through a review of the literature, the involvement of thrombophilias in obstetric pathologies.The literature shows a demonstrated association between fetal losses and biological anomalies related to thrombosis. However, this association is controversial for pre-eclampsia and not found for fetal hypotrophy. Finally, there is very little…mehr

Produktbeschreibung
Pregnancy is a physiological situation that disturbs the haemostatic balance and therefore constitutes an additional thromboembolic risk in thrombophilic women, incriminated in the occurrence of multiple complications. Thus, our research work aims to explore, through a review of the literature, the involvement of thrombophilias in obstetric pathologies.The literature shows a demonstrated association between fetal losses and biological anomalies related to thrombosis. However, this association is controversial for pre-eclampsia and not found for fetal hypotrophy. Finally, there is very little documentation of this association for in utero growth retardation and retro placental hematoma.An early etiological diagnosis of these constitutional thrombophilias is recommended for adequate management.
Autorenporträt
Dr. Rim Frikha; MD-PhD, Profesor Asociado de Medicina, Histología-EmbriologíaEspecialista en genética molecular en onco-hematologíaUniversidad de Sfax-Facultad de Medicina; Sfax-TúnezCHU Hedi Chaker- Servicio de Genética Médica ; Sfax-Túnez