Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods.…mehr
Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods.
Dr. Aschner serves as the Harold and Muriel Block Chair in Molecular Pharmacology at Albert Einstein College of Medicine. He served on numerous toxicology panels (Institute of Medicine, US Environmental Protection Agency, Center for Disease Control), and is a member of the Neurotoxicology and Alcohol study section (NIH). Research in our lab focuses on the following topics: (1) Modulation of C. elegans genes (aat, skn-1, daf-16) that are homologous to mammalian regulators of MeHg uptake and cellular resistance will modify dopaminergic neurodegeneration in response to MeHg exposure. (2) Under conditions of MeHg-induced oxidative stress, Nrf2 (a master regulator of antioxidant responses) coordinates the upregulation of cytoprotective genes that combat MeHg-induced oxidative injury, and that genetic and biochemical changes that negatively impact upon Nrf2 function increase MeHg's neurotoxicity. (3) PARK2, a strong PD genetic risk factor, alters neuronal vulnerability to modifiers of
cellular Mn status, particularly at the level of mitochondrial dysfunction and oxidative stress. Our studies are designed to (1) shed novel mechanistic insight into metal-induced neurodegeneration; (2) identify targets for genetic or pharmacologic modulation of neurodegenerative disorders; (3) increase knowledge of the pathway involved in oxidative stress; (4) develop improved research models for human disease using knowledge of environmental sciences.
Inhaltsangabe
Preface Roberto G. Lucchini 1. Current evolution of neurobehavioral methods Maryse F. Bouchard, Diane S. Rohlman, Carola Tuerk, Hana-May Eadeh, Trisha Saha and W. Kent Anger 2. Cognitive impact of exposure to airborne particles captured by brain imaging Somaiyeh Azmoun, Jenny Diaz, Cheuk Y. Tang, Megan Horton, Sean A.P. Clouston, Ben J. Luft, Evelyn J. Bromet, Sam Gandy, Donatella Placidi, Claudia Ambrosi, Lorella Mascaro, Carlo Rodella, Barbara Paghera, Roberto Gasparotti, Jeremy W. Chambers, Kim Tieu and Roberto G. Lucchini 3. Clinical evaluation and differential diagnosis of neurotoxic disease Jonathan Rutchik and Marcia H. Ratner 4. Aerotoxic syndrome: A new occupational disease caused by contaminated cabin air? G. Hageman, SJ Mackenzie Ross, J. Nihom and G. van der Laan 5. Occupational neurotoxicity of organic solvents Christoph van Thriel and William K. Boyes 6. Pesticides Diane S. Rohlman, James R. Olson, Ahmed Ismail, Matthew R. Bonner, Gaafar Abdel Rasoul and Olfat Hendy 7. Diagnosis and management of occupational and environmental carbon monoxide neurotoxicity Jonathan Rutchik and Marcia H. Ratner 8. Mercury neurotoxicity in gold miners Maria Elena Crespo-Lopez, Marcus Augusto-Oliveira, Amanda Lopes-Araújo, Letícia Santos-Sacramento, José Rogério Souza-Monteiro, Felipe Farias da Rocha and Gabriela de Paula Arrifano
Preface Roberto G. Lucchini 1. Current evolution of neurobehavioral methods Maryse F. Bouchard, Diane S. Rohlman, Carola Tuerk, Hana-May Eadeh, Trisha Saha and W. Kent Anger 2. Cognitive impact of exposure to airborne particles captured by brain imaging Somaiyeh Azmoun, Jenny Diaz, Cheuk Y. Tang, Megan Horton, Sean A.P. Clouston, Ben J. Luft, Evelyn J. Bromet, Sam Gandy, Donatella Placidi, Claudia Ambrosi, Lorella Mascaro, Carlo Rodella, Barbara Paghera, Roberto Gasparotti, Jeremy W. Chambers, Kim Tieu and Roberto G. Lucchini 3. Clinical evaluation and differential diagnosis of neurotoxic disease Jonathan Rutchik and Marcia H. Ratner 4. Aerotoxic syndrome: A new occupational disease caused by contaminated cabin air? G. Hageman, SJ Mackenzie Ross, J. Nihom and G. van der Laan 5. Occupational neurotoxicity of organic solvents Christoph van Thriel and William K. Boyes 6. Pesticides Diane S. Rohlman, James R. Olson, Ahmed Ismail, Matthew R. Bonner, Gaafar Abdel Rasoul and Olfat Hendy 7. Diagnosis and management of occupational and environmental carbon monoxide neurotoxicity Jonathan Rutchik and Marcia H. Ratner 8. Mercury neurotoxicity in gold miners Maria Elena Crespo-Lopez, Marcus Augusto-Oliveira, Amanda Lopes-Araújo, Letícia Santos-Sacramento, José Rogério Souza-Monteiro, Felipe Farias da Rocha and Gabriela de Paula Arrifano
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Shop der buecher.de GmbH & Co. KG Bürgermeister-Wegele-Str. 12, 86167 Augsburg Amtsgericht Augsburg HRA 13309