On the road from Histones to Chromosome - Bhat, Younus Ahmad;Batool, Asiya;Aashaq, Sabreena
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Eukaryotes and prokaryotes are the two superkingdoms of organisms. Eukaryotic chromosome is uninemic-that is, contains one double helix of DNA. The DNA must be available for the preinitiation complex to form,with its RNA polymerase and general transcription factors.It appears that DNA wrapped around nucleosomes is often not accessible for the formation of the preinitiation complex, but is available for recognition by transcription activating proteins, also called specific transcription factors.We concentrate on the roles of histones, their regulation and chromatin remodeling in gene expression.…mehr

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Produktbeschreibung
Eukaryotes and prokaryotes are the two superkingdoms of organisms. Eukaryotic chromosome is uninemic-that is, contains one double helix of DNA. The DNA must be available for the preinitiation complex to form,with its RNA polymerase and general transcription factors.It appears that DNA wrapped around nucleosomes is often not accessible for the formation of the preinitiation complex, but is available for recognition by transcription activating proteins, also called specific transcription factors.We concentrate on the roles of histones, their regulation and chromatin remodeling in gene expression.
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Autorenporträt
Younus Ahmad Bhat has done MSc in Clinical Biochemistry, from University of Kashmir. He has received his Mphil degree from University of Kashmir. He has contributed extensively to the world literature with publications appearing in reputed Journals. The author is presently doing PhD in Chromatin Biology.