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Oncogenes play a major role in the development and progression of the cancer. As many researches are going on related to the pivotal role played by the oncogenes in the cancer development, which remains unclear till now. In the future, therapeutic procedures, oncogenes are important. Hence in this book we acquired various researchers opinions related to the tumor suppressor genes, which will be useful for the further review. We mainly considered and concentrated on the recent advances related to oncogenic therapy rather than the basic mechanism.