V rabote proveden analiz literatury po sushchestvuyushchim metodam opredeleniya davleniya tseli pri glaukome. Na osnovanii sobstvennykh obsledovaniy rekomenduetsya ispol'zovanie novogo metoda opredeleniya tselevogo davleniya. On uchityvaet individual'nye biomekhanicheskie svoystva korneoskleral'noy obolochki glaza i pozvolyaet podobrat' adekvatnuyu gipotenzivnuyu terapiyu, obespechivayushchuyu stabilizatsiyu glaukomnogo protsessa i sokhrannost' zritel'nykh funktsiy. Dlya ob"ektivnoy otsenki i svoevremennoy diagnostiki nachal'nykh glaukomnykh izmeneniya i predotvrashchenie progressirovaniya glaukomnogo protsessa predlagaetsya original'nyy biomekhanicheskiy koeffitsient, rasschitannyy na osnovanii gisterezisa i tolshchiny rogovitsy. Obsuzhdaetsya vpervye vyyavlennaya strukturno-biomekhanicheskaya i biokhimicheskaya patologiya sklery glaz s glaukomoy, a imenno izbytochnoe formirovanie v kollagenovykh strukturakh poperechnykh khimicheskikh svyazey, povyshayushchikh zhestkost' sklery.Eto predstavlyaetsya sushchestvennym shagom v ponimanii patogeneticheskikh mekhanizmov glaukomy, i mozhet sluzhit' osnovaniem dlya razrabotki novykh kriteriev diagnostiki i patogeneticheskoy terapii, napravlennoy na regulyatsiyu biomekhanicheskikh kharakteristik sklery.