An osmotic drug delivery system, also known as an osmotic pump, is a system that releases drugs over time through a semi permeable membrane that contains one or more ports. The system is made up of a core containing a drug and an osmogen which is coated with the membrane. The osmogen absorbs water from the surrounding medium through the membrane, which is permeable to water but impermeable to the drug. The drug is released as a solution or suspension over time. Osmotic drug delivery systems are a promising strategy for controlled drug delivery. The system is independent of gut factors and is regulated only by the nature of the formulation. Most drugs used in this type of system have a short half-life, are very potent, and require to be used over long durations.
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