Oral Pigmented Lesions
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The mucous membrane that lines the oral cavity consists of a layer of stratified squamous epithelium and a subepithelial layer, the lamina propria, which consists of a fibrous connective tissue and contain capillaries, nerves and the minor salivary glands. It is not uniformly colored and several degrees of chromatic variation may be observed in physiologic and pathologic conditions. Oral subsites are characterised by different structural colors, depending on degree of keratinization, numbers and melanogenic activity of melanocytes, vascularization and type of submucosal tissue. Pigmented lesio...
The mucous membrane that lines the oral cavity consists of a layer of stratified squamous epithelium and a subepithelial layer, the lamina propria, which consists of a fibrous connective tissue and contain capillaries, nerves and the minor salivary glands. It is not uniformly colored and several degrees of chromatic variation may be observed in physiologic and pathologic conditions. Oral subsites are characterised by different structural colors, depending on degree of keratinization, numbers and melanogenic activity of melanocytes, vascularization and type of submucosal tissue. Pigmented lesions are commonly found in the mouth. Such lesions represent a variety of clinical entities, ranging from physiologic changes (e.g., racial pigmentation) to manifestations of systemic illnesses (e.g., Addison's disease) and malignant neoplasms (e.g., melanoma and Kaposi's sarcoma). Therefore, an understanding of the causes of mucosal pigmentation and appropriate evaluation of the patient are essential.
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