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Orofacial cleft is one of the common congenital abnormalities. It has a negative impact on the life of an individual and results in decreased quality of life. Etiology includes interaction of environmental and genetic factors. Knowledge on orofacial clefts should be promoted to create awareness on its preventive measures. This book "Orofacial Clefts" explains the Cleft pathogenesis, various types of orofacial clefts, their anatomy and their management.