Osmosis Jones is the soundtrack to the 2001 film, Osmosis Jones. It was released on August 7, 2001 through Atlantic Records and consisted of hip hop and contemporary R&B. The soundtrack failed to make it to any Billboard charts, but Trick Daddy's single "Take It to da House" managed to make it to 88 on the Billboard Hot 100. Osmosis Jones is a 2001 live-action/animated Comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the live-action segments. Unusual in this genre, the live-action characters never meet the animated characters.