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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Osteogenesis imperfecta (OI), also known as brittle bone disease or Lobstein syndrome, is a genetic bone disorder. OI sufferers are born with defective connective tissue, or without the ability to make it, which is generally because of a deficiency of Type-I collagen. Due to this, the sufferers can easily break their bones and have hundreds of fractures in their lifetime...