Otis Wayne Grigsby, Jr. (born November 19, 1980 in San Antonio, Texas) is an American football defensive end who is a free agent of the National Football League. He was signed by the Miami Dolphins as an undrafted free agent in 2003. He played college football at Kentucky. Grigsby has also been a member of the Atlanta Falcons and Carolina Panthers. Grigsby attended Judson High School in Converse, Texas and was a student and a letterman in football and basketball. In football, as a senior, he started as a linebacker and was a first team All-State selection. In basketball, he was an All-District Honorable Mention selection and an All-City selection. Otis Grigsby graduated from Judson High School in the top 10 percent of his class.