Samuel Antwi-Baffour

Overview of Malaria Infection and Haematological Indices in Africa

Understanding Malaria in Tropical Africa: Transmission, Infection, and Hematological Indices

• Broschiertes Buch

Produktbeschreibung

Malaria, a severe parasitic disease transmitted by Anopheles mosquitoes, is caused by various Plasmodium species, with P. falciparum and P. vivax posing the greatest threat. While most infections are uncomplicated, a small percentage progresses to severe malaria, characterized by disruptions in immune cell profiles and increased cytokine levels. Severe P. falciparum malaria is associated with elevated plasma cytokines, T cell lymphopenia, and impaired T cell function. Treatment aims to restore immune cell balance, particularly CD3+, CD4+, and CD8+ cells. Protective immunity involves CD8+ T cells and cytokines like IFN-Gamma and TNF, while CD4+ T cells combat erythrocytic parasites through cytokine secretion and macrophage activation. Regulatory T cells also play a role, highlighting the importance of cytokine balance in malaria. Additionally, factors like antigen affinity influence T helper lymphocyte differentiation, affecting immune responses to the disease.

Produktdetails

• Verlag: Scholars' Press
• Seitenzahl: 84
• Erscheinungstermin: 22. Oktober 2024
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 143g
• ISBN-13: 9786206772170
• ISBN-10: 6206772179
• Artikelnr.: 72135523

Autorenporträt

Prof. Samuel Antwi-Baffour is a Professor of Immunology and the Dean of the School of Biomedical and Allied Health Sciences, University of Ghana. He holds a BSc and MSc in Biomedical Science and a Doctor of Philosophy degree in Immunology all from London Metropolitan University, London, UK. He also belongs to various Scientific Associations.