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Oxidative Injury in Dermatopathology
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This book will serve as a valuable source of information for cutaneous biologists, dermatologists, and biomedical scientists interested in free radicals and reactive oxygen species and their role in skin pathology. It covers all aspects of oxidative stress, including its importance in basic pathologic processes, as well as in skin diseases, dermatopharmacology and dermatotoxicology. A wealth of references is also provided. In the introduction, the physicochemical properties and production and target sites of reactive oxidants in the skin are discussed. The antioxidant systems of the skin are t...
This book will serve as a valuable source of information for cutaneous biologists, dermatologists, and biomedical scientists interested in free radicals and reactive oxygen species and their role in skin pathology. It covers all aspects of oxidative stress, including its importance in basic pathologic processes, as well as in skin diseases, dermatopharmacology and dermatotoxicology. A wealth of references is also provided. In the introduction, the physicochemical properties and production and target sites of reactive oxidants in the skin are discussed. The antioxidant systems of the skin are then described, and the participation of oxidants and antioxidants in basic pathophysiologic events is analyzed. Finally, specific aspects of oxidative injury in selected skin diseases, pharmacology and toxicology are investigated. Dieses Buch wendet sich insbesondere an klinische Dermatologen und Forscher, die sich mit oxidativen Vorgängen in der Haut beschäftigen. Erstmals wird der aktuelle Wissensstand in diesem sich schnell entwickelnden Forschungsgebiet zusammengefaßt. Die Themengebiete umfassen die Beteiligung oxidativer Prozesse bei der Entstehung verschiedener Hauterkrankungen, Angriffsort und Wirkungsweise freier Sauerstoffradikale und anderer reaktiver Sauerstoff-Formen. Eine umfangreiche Literaturübersicht auf neuestem Stand ergänzt diesen Band.