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This Book markedly emphasizes the nuances of Ozone in dentistry along with shedding light on medical applications. A sincere effort been made to describe the comprehensive aspect supported with studies on Ozone. Minimal Invasive procedures a part of recent trends in dentistry have demanded the use of OZONE. Its wide array of use in multifactorial dental infections without any known severe side effects have led to its importance. Ozone gas is immunostimulating, potent analgesic, detoxicating, antimicrobial, bio-energetics and has biosynthetic properties as it causes activation of the metabolism of carbohydrates, proteins and lipids. Ozonated water and olive oil forms an ideal delivery system as they have the capacity to entrap and then release oxygen/ozone. The use of OZONE, which has no effects on environment also is future of green dentistry for greener tomorrow.