Transition metals (Pd, Ni, Cu, Fe, Au) have played significant role in organic chemistry for creating organic molecules. One metal palladium with different ligands is being used as efficient catalyst for C-C bond formation. Palladium catalyzed reactions are used in the synthesis of many natural products, pharmaceutical drugs and advance materials. In this research work, Heck, Suzuki and Sonogashira reactions of di and tri halogenated and dihydroxy heterocycles (benzothiophene, pyrazine, quinoxaline, pyrimidine, furan and flavone) with photophysical properties of some alkynylated products of Pyrimidines and furans, have been studied in detail.