High Quality Content by WIKIPEDIA articles! Palpebral fissure is the anatomic name for the separation between the upper and lower eyelids. In the adult this measures about 10mm vertically and 30 mm horizontally. It can be reduced in horizontal size by fetal alcohol syndrome. In Trisomy 9 the palpebral fissures can be upslanting. The fissure may be increased in vertical height in Graves' disease, which is manifested as Dalrymple's sign. It is one of the numerous symptom of genetic disorders like Cri-du-chat.
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