Parents' satisfaction and involvement are vital for the judgment of healthcare interventions. Parents were satisfied by participating in their child's health, thereby enhancing adherence to the therapeutic regimen and understanding medical information. Parents' participation in their child's care is a new approach. An effective communication between parents and health professionals is vital for parent satisfaction and quality of care. The aim of this book was to determine the level of parental satisfaction and involvement and its associated factors at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.