Parkinson¿s Disease. From Clinical Aspects to Molecular Basis

Ed. by Toshiharu Nagatsu, Hirotaro Narabayashi and Mitsuo Yoshida

• Broschiertes Buch

Produktbeschreibung

In diesem Buch werden die wichtigsten Aspekte der Parkinson-Krankheit, die für ihre Diagnose und Behandlung wesentlich sind, dargestellt.

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Produktdetails

• Key Topics in Brain Research
• Verlag: Springer / Springer Vienna / Springer, Wien
• Artikelnr. des Verlages: 978-3-211-82272-2
• 1991.
• Seitenzahl: 232
• Erscheinungstermin: 6. November 1991
• Englisch
• Abmessung: 229mm x 152mm x 13mm
• Gewicht: 392g
• ISBN-13: 9783211822722
• ISBN-10: 3211822720
• Artikelnr.: 31114195

Inhaltsangabe

Tyrosine hydroxylase in relation to Parkinson's disease: a historical overview and future prospect.- Discovery of dopamine deficiency and the possibility of dopa therapy in Parkinsonism.- Genes of human catecholamine-synthesizing enzymes.- Receptor alterations in Parkinson's disease.- Second messengers in Parkinson's disease.- Mitochondrial energy crisis as a mechanism for nigral cell death.- Tetrahydroisoquinoline (TIQ) and its derivatives: the occurrence and the metabolism in the brain, and the effects on catecholamine metabolism.- Can tetrahydroisoquinoline (TIQ) or N-methyl-TIQ produce parkinsonism?.- Relationship between TIQs and Parkinson's disease.- Sparteine oxidation in patients with early- and late-onset of Parkinson's disease.- Association of Xba I allele (Xba I 44kb) of the human cytochrome P-450dbI (CYP2D6) gene in Japanese patients with idiopathic Parkinson's disease.- Immunological aspects of neural transplantation.- Epidemiology of Parkinson's disease-interplaying genes and environmental factors.- Topics of special interest in research of Parkinson's disease.- Importance of juvenile parkinsonism in elucidating the pathogenesis of Parkinson's disease.- Dopa-unresponsive pure akinesia or freezing.- Hereditary progressive dystonia with marked diurnal fluctuation.- Positron emission tomographic study in Parkinson's disease-rigid vs tremor type.- Role of stereotaxic surgery in treatment of Parkinson's disease.- L-threo-DOPS-implications for pathophysiology of parkinsonian symptoms chronically treated with L-DOPA.Contents: Tyrosine hydroxylase in relation to Parkinson's disease: a historical overview and future prospect.- Discovery of dopamine deficiency and the possibility of dopa therapy in Parkinsonism.- Genes of human catecholamine-synthesizing enzymes.- Receptor alterations in Parkinson's disease.- Second messengers in Parkinson's disease.- Mitochondrial energy crisis as a mechanism for nigral cell death.- Tetrahydroisoquinoline and its derivatives: the occurence and the metabolism in the brain, and the effects on catacholamine metabolism.- Can tetrahydroisoquinoline (TIQ) or N-methyl-TIQ produce parkinsonism?- Relationship between TIQs and Parkinson's disease.- Sparteine oxidation in patients with early- and late-onset of Parkinson's disease.- Association of Xba I allele (Xba I 44Kb) of the human cytochrome P-450dbI (CYP2D6) gene in Japanese patients with idiopathic Parkinson's disease.- Immunological aspects of neural transplantation.
Epidemiology of Parkinson's disease interplaying genes and environmental factors.- Topics of special interest in research of Parkinson's disease.- Importance of juvenile parkinsonism in elucidating the pathogenesis of Parkinson's disease.- Dopa-unresponsive pure akinesia or freezing.- Hereditary progressive dystonia with marked diurnal fluctation.- Positron emission tomographic study in Parkinson's disease - rigid vs tremor type.- Role of stereotaxic surgery in treatment of Parkinson's disease.- L-threo-DOPS-implications for pathophysiology of parkinsonian symptoms chronically treated with L-DOPA.- Subject Index.