Pathogenesis and Treatment of Diabetes Mellitus

Herausgegeben:Radder, J. K.; Lemkes, H.H.P.J.; Krans, H. M. J.

• Broschiertes Buch

Produktbeschreibung

In this book on diabetes mellitus both the pathogenesis and treat ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out break of the disease, the destructive process has already been active for years.

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Produktdetails

• Verlag: Springer / Springer Netherlands
• Artikelnr. des Verlages: 978-94-010-8411-6
• Softcover reprint of the original 1st ed. 1986
• Seitenzahl: 188
• Erscheinungstermin: 27. September 2011
• Englisch
• Abmessung: 235mm x 155mm x 11mm
• Gewicht: 295g
• ISBN-13: 9789401084116
• ISBN-10: 9401084114
• Artikelnr.: 39498169

Inhaltsangabe

1.: Pathogenesis of Diabetes Mellitus.- Section 1.1.: Type I Diabetes Mellitus.- 1.1.1.: Introduction: Type I Diabetes Mellitus.- 1.1.2.: Autoimmune pathogenesis of viral diabetes.- 1.1.3.:Immunological features of insulin-dependent diabetes mellitus.- 1.1.4.:Genetic counselling in Diabetes Mellitus.- Section 1.2.: Type II Diabetes Mellitus.- 1.2.1.: Introduction: Pathogenesis of type II Diabetes Mellitus.- 1.2.2.:Insulin secretion in noninsulin-dependent Diabetes Mellitus.- 1.2.3.: Insulin antagonism.- 1.2.4.: The contribution of the central nervous system to the regulation of insulin release and the stabilization of blood glucose.- 1.2.5.: Cellular insulin resistance.- 2.: Treatment of Diabetes Mellitus.- Section 2.1.: Diet and hypoglycaemic agents.- 2.1.1.: Introduction: Diet and hypoglycaemic agents.- 2.1.2.: Diet and Diabetes.- 2.1.3.: Oral hypoglycaemic drugs.- Section 2.2.: Insulin.- 2.2.1.: Introduction: Insulin treatment.- 2.2.2.: Hyperinsulinaemia.- 2.2.3.: Insulin: The physiological basis of its administration.- 2.2.4.: Diabetes Technology: From the pump to the microprocessor.- Section 2.3.: Pancreas transplantation.- 2.3.1.: Introduction: Pancreas transplantation.- 2.3.2.: Current state of pancreas transplantation.- Index of subjects.