Novartis Foundation Symposium

Pathological Pain

From Molecular to Clinical Aspects
Herausgeber: Chadwick, Derek J; Goode, Jamie A

• Gebundenes Buch

Produktbeschreibung

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.

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Produktdetails

• Novartis Foundation Symposia 261
• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 288
• Erscheinungstermin: 20. August 2004
• Englisch
• Abmessung: 234mm x 155mm x 18mm
• Gewicht: 576g
• ISBN-13: 9780470869109
• ISBN-10: 0470869100
• Artikelnr.: 13937223

Autorenporträt

Derek J. Chadwick and Jamie A. Goode are editors for Pathological Pain: From Molecular to Clinical Aspects and other scientific titles.

Inhaltsangabe

Chair's Introduction (Takao Kumazawa).
Regulation Mechanisms of Vanilloid Receptors (Makoto Tominagaet, et al.).
Sodium channels and neuropathic pain (Jin Mo Chung and Kyungsoon Chung).
Ion channel activities implicated in pathological pain (John N. Wood, et al
.).
General Discussion I.
Chronic pain and microglia: the role of ATP (Kazuhide Inoue, et al.).
Neurotrophic influences on neuropathic pain (Stephen B. McMahon and William
B. J. Cafferty).
Changes in DRG neurons and spinal excitability in neuropathy (Koichi
Noguchi, et al.).
Functional reorganization of the spinal pain pathways in developmental and
pathological conditions (M. Yoshimura, et al.).
Central plasticity in pathological pain (Min Zhuo).
General Discussion II.
Anti-opioid systems in morphine tolerance and addiction: locus-specific
involvement of nociceptin and NMDA receptor (Hiroshi Ueda).
Chronic morphine-induced plasticity among signalling molecules (Alan R.
Gintzler and Sumita Chakrabarti).
Opioid tolerance and neuroplasticity (Jianren Mao).
General Discussion III.
A mechanism-based understanding of bone cancer pain (Patrick W. Mantyh).
Mechanistic and clinical aspects of complex regional pain syndrome
(CRPS)(Ralf Baron).
Cortical pathophysiology of chronic pain (A. Vania Apkarian).
Final Discussion: Translating basic research to the clinic.
Index of contributors.
Subject index.

Rezensionen

"...an excellent book to review the electrophysiological and molecular aspects of pathological pain...can be of great value to both basic scientists and clinicians." ( Annals of Neurology , August 2005)