Pathology of Pediatric Gastrointestinal and Liver Disease
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Ten years have elapsed since the printing of the second edition of this book. Since then there's been a veritable explosion of information coming mainly from the field of molecular diagnostics, which bear particular importance in the classification and treatment of Infantile enteropathies, disorders associated with immunodeficiencies, the classification of intestinal polyps and polyposis syndromes in childhood, cholestatic and metabolic disorders of childhood, liver tumors and transplantation pathology, all of which were major subjects explored in our previous editions. In this updated third…mehr

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Produktbeschreibung
Ten years have elapsed since the printing of the second edition of this book. Since then there's been a veritable explosion of information coming mainly from the field of molecular diagnostics, which bear particular importance in the classification and treatment of Infantile enteropathies, disorders associated with immunodeficiencies, the classification of intestinal polyps and polyposis syndromes in childhood, cholestatic and metabolic disorders of childhood, liver tumors and transplantation pathology, all of which were major subjects explored in our previous editions. In this updated third edition, most of the chapters have been extensively revised to incorporate updated understanding in pathogenesis and terminology. For example, the widespread use of genetic panels and next generation sequencing in the diagnosis of cholestatic disorders of infancy and childhood, not widely available when the last edition was being prepared, prompted the writing of an entirely new chapter reflecting these advances by a new set of authors. Similarly, progress in diagnosis and classification of liver tumors justified an entirely new chapter on liver tumors that incorporates newer patient stratification in treatment protocols and reflects the new WHO classification of liver tumors.

Pathology of Pediatric Gastrointestinal and Liver Disease 3rd Edition provides the pediatric pathologist, the GI or general pathologist, and the pediatric gastroenterologist with the most complete and current reference on the subject. It includes in-depth discussions on disorders and issues that are frequently encountered but for which up-to-date information is often not readily available, as well as infrequent disorders unique or specific to children that are not covered in standard texts.
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Autorenporträt
Pierre A. Russo, MD, is Professor of Pathology and Laboratory Medicine at the University of Pennsylvania School of Medicine. He has served as Chief of the Division of Anatomic Pathology, at the Children's Hospital of Philadelphia.. Additionally, Professor Russo is Co-Chair of the Pathology Committee for the Childhood Liver Disease Research and Education Network (ChiLDREN). He is also Editor-in-Chief of the journal Pediatric and Developmental Pathology. He is board certified by the American Board of Pathology/Anatomic and Clinical Pathology and the American Board of Pathology/Pediatric Pathology. His special interests are the pathology of hepatobiliary and digestive disorders in children, and his research has focused on the mechanisms of cholestasis and on bile duct disorders, having published extensively on these and related topics . Eduardo D. Ruchelli, MD, is Associate Professor of Pathology and Laboratory Medicine at the University of Pennsylvania School of Medicine and Attending Pathologist at the Children's Hospital of Philadelphia. He is board certified by the American Board of Pathology/Anatomic and Clinical Pathology and the American Board of Pathology/Pediatric Pathology. His special interests include fetal and perinatal pathology, pathologic evaluation of the pancreas in congenital hyperinsulinism, and eosinophilic esophagitis. He has published widely on these and other subjects in peer-reviewed journals. David A. Piccoli, MD, is Professor of Pediatrics at the University of Pennsylvania Perelman School of Medicine. He has served asChief of the Division of Gastroenterology, Hepatology, and Nutrition at the Children's Hospital of Philadelphia,  Director of the Fred and Suzanne Biesecker Pediatric Liver Center and Associate Chair for Information, Department of Pediatrics, The Children's Hospital of Philadelphia. He is board certified by the American Board of Pediatrics and the American Board of Pediatrics/Pediatric Gastroenterology. His special interests include Alagille syndrome, bile duct disorders, and inflammatory bowel disease, and he has published extensively on these and other topics. Professor Piccoli has also been the recipient of various awards, including the Outstanding Leadership Award from the Crohn's and Colitis Foundation of America, the Leadership Award from the American Liver Foundation, the Murray Davidson Award from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, and the Master Clinician Award from the Perelman School of Medicine at the University of Pennsylvania.