This comprehensive review begins by describing the normal pancreas and its anatomical variants. There follows detailed discussion of pathological changes in pancreatic diseases and the responses produced by various systemic conditions that affect the pancreas directly or indirectly. Although emphasis is placed on macroscopic and historical changes, reflecting the expertise of the authors, the aetiology and and pathogenesis of many pancreatic disorders are considered in detail. The effects of infectiv e and non-infective pancreatitis, various cancerous states and effects of parasitic infections are all covered making this an indispensable reference for pathologist and clinician alike. As with the first edition this co-authored update combines succinct text with liberal use of high quality photographs, forming a balanced reference which not only contains a wealth of knowledge but is also of practical use to pathologists and gastroenterologists.