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High Quality Content by WIKIPEDIA articles! A patient-reported outcome or PRO is a questionnaire used in a clinical trial or a clinical setting, where the responses are collected directly from the patient. PRO is an umbrella term that covers a whole range of potential types of measurement but is used specifically to refer to questionnaires completed by the patient. PRO data may be collected via self-administered questionnaires completed by the patient themselves or via interviewer-administered questionnaires. The latter will only qualify as a PRO where the interviewer is gaining the patient s views, not where the interviewer uses patient responses to make a professional assessment or judgment of the impact of the patient s condition. Thus, PROs are a means of gathering patient rather than clinical or other views on the content covered by the questionnaire.