The early stages of kidney failure are asymptomatic and mostly unknown. It can be identified by checking the serum creatinine levels and glomerular filtration rate based on the age and other clinical conditions. The 5th stage of kidney failure is also known as an end-stage renal disease (ESRD) in which the GFR rate is <15 ml/min and the patient should be treated with Renal Replacement Therapy and Dialysis. The GFR rate can be calculated by using various formulas that consider serum creatinine levels, body weight, age; they are Cock croft-gault formula, Modification of Diet in Renal Disease formula (MDRD), CKD-EPI formula and Mayo Quadratic formula. This study is based to assess the comorbid conditions of diabetes, hypertension and other cardiovascular events associated with various levels of renal function.