PD-L1 and Hodgkin¿s Lymphoma - Abdulrahman, Mohammed
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In Hodgkin Lymphoma (HL), immunohistochemical expression of programmed death ligand 1 (PD-L1) is found in 67.5% of HL cases and 35% of the tumor micro-environment. However, there is no significant association between PD-L1 expression and the presence of EBV latent membrane protein-1 (LMP-1). Only 29.6% of patients with positive PD-L1 expression also show positive EBV LMP-1. Additionally, no significant associations were identified between PD-L1 expression and HL subtype, age, and gender. On the other hand, EBV LMP-1 immunohistochemical expression is significantly associated with male gender…mehr

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Produktbeschreibung
In Hodgkin Lymphoma (HL), immunohistochemical expression of programmed death ligand 1 (PD-L1) is found in 67.5% of HL cases and 35% of the tumor micro-environment. However, there is no significant association between PD-L1 expression and the presence of EBV latent membrane protein-1 (LMP-1). Only 29.6% of patients with positive PD-L1 expression also show positive EBV LMP-1. Additionally, no significant associations were identified between PD-L1 expression and HL subtype, age, and gender. On the other hand, EBV LMP-1 immunohistochemical expression is significantly associated with male gender (83.3%) and certain histological subtypes but reveals no statistically significant difference concerning the age of the patients.
Autorenporträt
I am a dedicated Medical Doctor with extensive experience in the healthcare sector, currently specializing as a Hematologist in Mosul, Iraq. I graduated from Mosul Medical University-Nineveh College of Medicine in 2012 and have since progressed through various roles, including Rotator Doctor, Primary Health Care Doctor & now Senior Hematologist.