This teaching manual for nursing students covers the safe and effective administration of medicines and the management of therapeutic regimens. With a focus on best practices, the manual details techniques for administering drugs intramuscularly, intravenously, subcutaneously, among others, and emphasizes the importance of accurate dosing and the correct selection of injection sites. Enriched with evidence-based guidelines and case studies, the manual also highlights effective communication with patients and the application of Virginia Henderson's principles for patient-centered care. This resource is essential for students seeking excellence in clinical practice and compassionate, informed care.