Richard Fine / Steven Webber / William Harmon (eds.)

Pediatric Solid Organ Transplantation

Herausgeber: Fine, Richard N; Olthoff, Kim M; Kelly, Deirdre A; Harmon, William E; Webber, Steven A

• Gebundenes Buch

Produktbeschreibung

Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference, to both the basic science and organ specific surgical technique and after care. This second edition has been extensively updated in light of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatric transplantation * A definitive reference for all those interested in improving the care and quality of life of children undergoing solid organ transplantation * Section on immunosuppression has been expanded by four chapters to include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy * A new section has been added on the many topics related to quality of life that effect survivors of pediatric transplantation * International editorial and contributor team represents a wide geographical range and contains both recognized leaders and emerging experts Whether you are an established sub-specialist in pediatric transplantation, a transplant surgeon, or a pediatric specialist in a related area, this book will answer all your questions about care of the pediatric patient before, during, and after transplantation.

Produktdetails

• Verlag: Wiley
• 2nd Revised edition
• Seitenzahl: 488
• Erscheinungstermin: 12. Februar 2007
• Englisch
• Abmessung: 282mm x 226mm x 30mm
• Gewicht: 1769g
• ISBN-13: 9781405124072
• ISBN-10: 1405124075
• Artikelnr.: 24305986

Autorenporträt

Professor Richard Fine, Professor and Chairman, Department of Paediatrics, State University of New York, USA Dr Steve Webber, Division of Cardiology, Children's Hospital of Pittsburgh, USA Dr William Harman, Associate Professor of Paediatrics, Harvard Medical School, Boston, USA

Inhaltsangabe

Section 1 Immunology and Genetics.

1 The Immune Response to Organ Allografts.

2 Allorecognition Pathways.

3 Costimulation.

4 The HLA System and Histocompatibility Testing for OrganTransplantation.

5 Gene Polymorphisms and Pharmacogenomics.

6 Genomics and Proteomics as Research Tools.

7 Tolerance: A Review of its Mechanisms in the TransplantSetting.

Section 2 Immunosuppression and its Complications.

8 Mechanisms of Action of Immunosuppressive Agents.

9 Induction and Maintenance Immunosuppression.

10 Novel Immunosuppressants.

11 Therapies for the Allosensitized Patient.

12 Infections Post-Transplantation.

13 Post-Transplant Lymphoproliferative Disorders andMalignancy.

14 Organ Toxicities.

Section 3 Kidney Transplantation.

15 Historical Notes.

16 Recipient Characteristics.

17 Evaluation of the Candidate.

18 Donor Evaluation, Surgical Technique and PerioperativeManagement.

19 Pathology of the Kidney Allograft.

20 Post-Transplant Management.

21 Outcomes and Risk Factors.

Section 4 Liver Transplantation.

22 Historical Notes.

23 Recipient Characteristics.

24 Evaluation of the Candidate.

25 Donor Evaluation, Surgical Technique and PerioperativeManagement.

26 Pathology of the Liver Allograft.

27 Post-Transplant Management.

28 Outcomes and Risk Factors.

Section 5 Heart Transplantation.

29 Historical Notes.

30 Recipient Characteristics.

31 Evaluation of the Candidate.

32 Donor Evaluation, Surgical Technique and PerioperativeManagement.

33 Pathology of the Cardiac Allograft.

34 Post-Transplant Management.

35 Outcomes and Risk Factors.

Section 6 Lung and Heart-Lung Transplantation.

36 Historical Notes.

37 Recipient Characteristics.

38 Evaluation of the Candidate.

39 Donor Evaluation, Surgical Technique and PerioperativeManagement.

40 Pathology of the Lung Allograft.

41 Post-Transplant Management.

42 Outcomes and Risk Factors.

Section 7 Intestinal Transplantation.

43 Historical Notes.

44 Recipient Characteristics.

45 Evaluation of the Candidate.

46 Donor Evaluation, Surgical Technique and PerioperativeManagement.

47 Pathology of the Intestinal Allograft.

48 Post-Transplant Management.

49 Outcomes and Risk Factors.

Section 8 Special Issues after PediatricTransplantation.

50 Growth and Puberty.

51 Cognitive Development.

52 Psychosocial Adaptation and Adherence .

53 Pregnancy.

54 Gynecologic Issues.

55 Transition to Adult Care.

Index

Rezensionen

"This is a useful and readable reference for the pathologist, butmainly because of the basic scientific and clinical informationprovided rather than for its coverage of allograftpathology." (Pediatric and Developmental Pathology)

"This remains the only text devoted to pediatrictransplant issues and accomplishes the stated goals...It servesto fill a void in the field."
(Doody's Review Service)

"A comprehensive text written by experienced authors on allaspects of solid organ transplantation." (PaediatricEndocrinology Reviews)