Polyetheretherketone (PEEK) has emerged as a transformative material in the fields of dental implantology and prosthodontics, offering a metal-free alternative to traditional materials such as titanium and ceramics. This review provides a comprehensive exploration of PEEK's properties, applications, and potential in dental practice. Starting with an overview of the structure and chemistry of PEEK, the review delves into its manufacturing processes, highlighting how these contribute to its unique mechanical properties and biocompatibility. The versatility of PEEK extends beyond dentistry, with its use in various industries such as aerospace, automotive, and biomedical fields, underscoring its adaptability and durability. In dentistry, PEEK's application spans from implants and abutments to fixed and removable prostheses, offering significant advantages in terms of esthetics, patient comfort, and reduced allergic reactions. The review also examines the challenges associated with PEEK, particularly its bioinert nature, which can limit osseointegration, and discusses surface modification techniques aimed at enhancing its performance in implantology.