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  • Broschiertes Buch

Protein-protein interactions are involved in muscle contraction and signal transduction. This book describes how synthetic peptides may be used, much like antibodies, both as specific inhibitors and as molecular probes to explore the cognitive interfaces between interacting proteins and their functional significance. This offers the prospect of very selective intervention in cellular mechanisms. These timely contributions by several experts will appeal to the researchers in muscle physiology, cardiovascular pharmacology and cell biology who are interested in this new approach.

Produktbeschreibung
Protein-protein interactions are involved in muscle contraction and signal transduction. This book describes how synthetic peptides may be used, much like antibodies, both as specific inhibitors and as molecular probes to explore the cognitive interfaces between interacting proteins and their functional significance. This offers the prospect of very selective intervention in cellular mechanisms. These timely contributions by several experts will appeal to the researchers in muscle physiology, cardiovascular pharmacology and cell biology who are interested in this new approach.
Autorenporträt
Prof. Dr. med., Ph. D., Johann Caspar Rüegg, geb. 1930 in Zürich. Medizinstudium in Zürich und Dissertation beim Hirnphysiologen und Nobelpreisträger W. R. Hess. 1955-59 Studium der Biochemie an der Universität Cambridge, Promotion zum Ph. D. Bis 1967 Wissenschaftlicher Assistent am Max-Planck-Institut für Medizinische Forschung; 1963 Habilitation für Physiologische Chemie an der Universität Heidelberg; 1964/65 Senior Research Officer an der Universität Oxford; 1967-73 Wissenschaftlicher Rat und Professor am Institut für Zellphysiologie der Ruhr-Universität Bochum. 1973-1998 Ordinarius und Leiter des 2. Physiologischen Instituts der Universität Heidelberg. 1974 Adolf-Fick-Preis für Verdienste in Physiologie. 1981 Gastprofessor, seit 1985 Adjunct Professor in Physiologie an der Universität Cincinnati (Ohio). Seit 1998 korrespondierendes Mitglied der Schweizerischen Akademie der Medizinischen Wissenschaften.