Perforation Repair with Dental Pulp Stem Cells and DMP1 - Alsanea, Rajaa
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Perforations due to iatrogenic errors can compromise the tooth prognosis. There is still no ideal endodontic material in the market to be used in a perforation site. This study evaluates the ability of Dental Pulp Stem Cells (DPSCs) and Dentin Matrix Protein 1 (DMP1) impregnated within a collagen scaffold to induce dentin formation in a furcal perforation site. Under the conditions of this study, it may be concluded that DPSCs impregnated within a collagen scaffold can differentiate into odontoblast-like cells secreting a highly cellular, vascular, and mineralized matrix that can be the ground substance for dentin formation, in the presence of DMP1.…mehr

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Produktbeschreibung
Perforations due to iatrogenic errors can compromise the tooth prognosis. There is still no ideal endodontic material in the market to be used in a perforation site. This study evaluates the ability of Dental Pulp Stem Cells (DPSCs) and Dentin Matrix Protein 1 (DMP1) impregnated within a collagen scaffold to induce dentin formation in a furcal perforation site. Under the conditions of this study, it may be concluded that DPSCs impregnated within a collagen scaffold can differentiate into odontoblast-like cells secreting a highly cellular, vascular, and mineralized matrix that can be the ground substance for dentin formation, in the presence of DMP1.
Autorenporträt
Dr. Rajaa Alsanea got her Bachelor''s of Dental Surgery in 2005 from King Saud University in Riyadh, Saudi Arabia. She received her Masters of Oral Sciences and Certificate in Endodontics in 2008 from the University of Illinois at Chicago, United States. She is also an international best selling author (Girls of Riyadh) and a social activist.