The purpose of this study was at establish the relationship between goal setting and quality of lecturers' services. This was based on the deteriorating quality of lecturers' services in Makerere University. It was a cross-sectional survey, targeting academic staff in College of Humanity and Social Sciences (CHUSS), College of Commerce and Business Administration (CoBAMS) and College of Education and External Studies (CEES). These lecturers were selected using simple random sampling technique. Data was collected using a self-administered questionnaire. It was analyzed using Pearson's correlation coefficient index and regression analysis techniques. Results revealed that there was a highly positive significance impact between goal setting and quality of lecturers' services' (teaching, research supervision, writing and publication, and finally community services). It was hence concluded that goal setting is a strong predictor of quality of lecturers' services. Thus, a recommendation that once lecturers' quality of services is to be enhanced at Makerere University there should be high engagement of lecturers on boards, council, senate and others.