Personalized medicine is a medical model that involves the customization of healthcare with medical decisions, practices, and/or products being tailored to the individual patient need. The field of personalized medicine relies on genetic information, proteomic information and clinical patient characteristics to individualize treatment. Personalised medicine or precision medicine is a recent revolution in dentistry. one cut fits all concept is outdated but customised treatment is the latest concept. This book gives an indepth knowledge on pharmacogenomics and its importance.