Personalized and Stratified Therapy in Epilepsy

Herausgeber: Eyal, Sara; Ekstein, Dana

• Broschiertes Buch

Produktbeschreibung

Personalized and Stratified Therapy in Epilepsy highlights the individualized- and subgroup-based approaches in diagnosing, treating, and monitoring epilepsy. Whereas the term 'personalized medicine' is used to describe the focus on individual patients, 'stratified medicine' refers to the definition of population subgroups based on estimates of their differences in the etiology and prognosis of epilepsy, or response to treatment. The book describes the various aspects of personalized and stratified approaches in epilepsy, the potential of these approaches to improve the cost-effectiveness of epilepsy treatment, and barriers to their implementation. The book assists clinicians in rationally choosing the required diagnostic and treatment means for their patients, out of the abundance of available technologies and products. By doing so, they will provide better care, mitigating adverse events, expediting the reach of effective treatment, and reducing costs. The target audience is anyone involved in developing and delivering diagnostic means and treatment for people with epilepsy, including epileptologists, other neurologists, neurosurgeons, pharmacists, nurses, technicians, geneticists, researchers

Produktdetails

• Verlag: Elsevier Health Sciences
• Seitenzahl: 450
• Erscheinungstermin: 1. September 2022
• Englisch
• ISBN-13: 9780128173466
• ISBN-10: 0128173467
• Artikelnr.: 60138079

Inhaltsangabe

Section 1. Diagnosis 1. Classification 2. Seizures semiology 3. Genetic
testing 4. Electrophysiological studies 5. Imaging
Section 2. Drug treatment 6. When to start AEDs 7. Antiepileptic drug
treatments in children 8. Treating women with epilepsy 9. Antiepileptic
drugs in the elderly 10. When to stop treatment: individualized 11.
Pharmacogenetics in AED treatment 12. Between-patient variability in the
concentrations of antiepileptic drugs 13. Drug resistance: predicting who
will respond
Section 3. Non-pharmacological treatments 14. Pre-surgical evaluation 15.
Adult tailored surgical aspects 16. Pediatric tailored surgical aspects 17.
Neurostimulation
Section 4. Miscellaneous 18. Status epilepticus 19. SUDEP 20. Monitoring
sensors 21. Psychiatric co-morbidity 22. Neuropsychological evaluation 23.
Patient education
Section 5. Frontiers/research 24. Seizures prediction 25. Epilepsy
biomarkers 26. Can we personalize AED development? 27. Invasive monitoring
research 28. New treatment devices