This book deals with the serious social and economic impacts and consequences of undiscriminated use of pesticides by large agro-industrial activities in the Brazilian Amazon. The ongoing and increasing silent and invisible pollution and intoxication of the regional society with toxic Agro-chemical compounds needs to be discussed and revealed to avoid a tragic legacy for our future generations.The text is structured in four chapters: Chapter 1- Brazil, Amazon & The Use of Pesticides; Chapter 2- Runoff of Pesticides in the Amazon Hydrographic Basin; Chapter 3- Environmental, Social and Economic Impacts; and Chapter 4 - Strategies for Reducing the Use of Agrochemicals in The Amazon Basin.