pH Sensitive Responsive Gels - Geier, Roman
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There are many attempts to imrpove drug delivering systems. This work investigates a possible future way for targeted drug delivery. A gel out of water and oil phases that is able to change it's structure in dependence of the pH value. We were able to create phases which have enclosed water compartments at around pH 2. This structure changes to an open hexagonal phase at pH 7.4 which corresponds to the physiological pH. Succesful migration experiments have been carried out. This promissing technique is undergoing further research.

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Produktbeschreibung
There are many attempts to imrpove drug delivering systems. This work investigates a possible future way for targeted drug delivery. A gel out of water and oil phases that is able to change it's structure in dependence of the pH value. We were able to create phases which have enclosed water compartments at around pH 2. This structure changes to an open hexagonal phase at pH 7.4 which corresponds to the physiological pH. Succesful migration experiments have been carried out. This promissing technique is undergoing further research.
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Autorenporträt
Roman Geier, started his chemistry studies in 2006 at the University of Technology Graz in cooperation with the Karl-Franzen University within the socalled NAWI-Graz project. During his studies he was able to get a close insight in different research topics focusing on analytical, inorganic and physical chemistry.