Andrew Bond

Pharmaceutical Crystallography

A Guide to Structure and Analysis

• Broschiertes Buch

Produktbeschreibung

The pharmaceutical industry has become acutely aware of the importance of the solid state, but pharmaceutical scientists often lack specific training in topics related to solid-state structure and crystallography. This book provides needed support in this topical area. Taking an intuitive and informal approach to solid-state structure and crystallographic concepts, this book is written for anyone who needs a clear understanding of modern crystallography, with specific reference to small-molecule pharmaceutical solids. The author describes molecular crystals and crystal structures, symmetry, space groups, single-crystal and powder X-ray diffraction techniques and the analysis and interpretation of crystallographic data. Useful technical details are presented where necessary and case studies from the pharmaceutical literature put theory into a practical context. Written by an internationally leading figure and with its focus on molecular crystals, this book is equally applicable to chemists with a need to understand and apply X-ray crystal-structure determination.

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Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 292
• Erscheinungstermin: 24. Juli 2019
• Englisch
• Abmessung: 241mm x 161mm x 25mm
• Gewicht: 614g
• ISBN-13: 9781782629665
• ISBN-10: 1782629661
• Artikelnr.: 55506947

Inhaltsangabe

Pharmaceutical Solids
What Defines a Crystal?
Symmetry in Crystals
Space Groups
Planes and Crystal Morphology
Crystal Structures and Diffraction Patterns
Symmetry in Diffraction Patterns
Single-crystal X-ray Diffraction (Part 1)
Single-crystal X-ray Diffraction (Part 2)
Powder X-ray Diffraction
Solving X-ray Crystal Structures
Refining X-ray Crystal Structures
Disorder and Twinning
Crystallographic Results