S.K. Gupta (Hrsg.)

Pharmacology and Therapeutics in the New Millennium

Herausgegeben:Gupta, S. K.

• Gebundenes Buch

Produktbeschreibung

During the past several years tremendous advancements have been made in the field of pharmacology and therapeutics. While new therapeutic strategies are coming up, old ones are being improved by modifications, or being replaced with newer ones. The major topics covered in this book include: endothelins, current topics in cardiovascular research, molecular pharmacology, recent developments in cancer research, antioxidants, oxidants and human disease, herbal drugs, developments in neuropharmacology, myelin biology and demyelinating disease, pharmacovigilance, role of cytokines in health and disease, ocular pharmacology, detoxification of xenobiotics-biotransformation and transport, and several other topics of current interest.
The aim of this book is to fulfill the needs of the basic and clinical researchers as well as the students, particularly related to areas of current interest in pharmacology and therapeutics.

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Produktdetails

• Verlag: Narosa Publishing House, India / Springer / Springer Netherlands
• Artikelnr. des Verlages: 978-0-7923-7059-8
• 2001
• Seitenzahl: 764
• Erscheinungstermin: 30. September 2001
• Englisch
• Abmessung: 241mm x 160mm x 46mm
• Gewicht: 2730g
• ISBN-13: 9780792370598
• ISBN-10: 0792370597
• Artikelnr.: 23166429

Inhaltsangabe

Preface. 1. Endothelial Dysfunction and Vascular Disease; P.M. Vanhoutte.
2. Endothelin Receptors: Targets for drug development; A. Ray, et al. 3.
Role of Endothelins in Cardiovascular Disease; L.C. Katwa. 4. The Diabetic
Vasculature and Endothelin; D.A. Misurski, et al. 5. Beneficial Effects of
Renin-Angiotensin System Blockade in Myocardial Infarction; N.S. Dhalla, X.
Guo. 6. Role of Angiotensinogen in Human Hypertension; A. Kumar. 7.
Biological Function of Cardiac High Molecular Weight Calmodulin-binding
Protein; R. Kakkar, et al. 8. A Synthetic Calmodulin-binding Peptide
Unmasks Crucial Calmodulin Control of the Calcium-Pumping ATPase in Cardiac
Sarcoplasmic Reticulum; N. Narayanan, A. Xu. 9. Pharmacology of Vascular
Adenosine Receptors; M.A.H. Talukder, et al. 10. Aquaretic Vasopressin
Antagonists to Treat Chronic Hyponatremia; C.N. Corder, et al. 11.
Regional Differences in the Regulation of L-type Calcium Current in Heart
Cells; R. Kumar, et al. 12. Domoic Acid as a Tool in Molecular
Pharmacology; S.K. Sharma, N.S. Dhalla. 13. Molecular Basis of Adapted
Heart; D.K. Das, N. Maulik. 14. Gene Therapy and Renin-Angiotensin System;
A.S. Pachori, et al. 15. Transgenic and Knockout Mouse Models in New Drug
Discovery; V. Kumar. 16. Epidermal Growth Factor Receptor mRNA in Prostate:
Clinical Implications and Hormonal Regulation; V.L. Kumar. 17.
Angiogenesis: Concepts and Research Methodologies; S. Sengupta, S.K. Gupta.
18. Metabolism-Based Antifolate Drug Design: MDAM and MTREX; A. Amato, et
al. 19. Angiogenesis: A New Approach to Glutamine Related Therapy; P.
Maity, P. Bhattacharya. 20. Isolation and Characterization of Apoptosis
Resistant Mutants: Molecular Targets for Chemoprevention; N. Singh, et al.
21. High Exposure to Caffeine-Derived N-Nitroso Compounds as Carcinogenic
Risk for G.I.T. Cancers in Kashmir; M. Siddiqi. 22. Regulation of N
-Myristoyl-transferase in Human Colon Cancer; R.V.S. Rajala, et al. 23.
Differential Activation and Inhibition of Calmodulin-Dependent Cyclic
Nucleotide Phosphodiesterase Isozymes; R.K. Sharma. 24. Antioxidants in the
Prevention of Hypercholesterolemic Atherosclerosis; P. Lee, K. Prasad. 25.
Oxidative Stress and Aniline-Induced Splenic Toxicity; M.F. Khan, G.A.S.
Ansari. 26. Efficacy of High Dose Multiple Antioxidants as an Adjunct to
Standard Cancer Therapy; K.N. Prasad, et al. 27. Carotenoid/Retinol Dosage
in Prevention/Treatment of Second Primary Cancer, Cyclical Mastodynia
Syndrome and AIDS; L. Santamaria, A. Bianchi-Santamaria. 28. Complimentary
Medicines and 21st Century Therapeutics: Challenges for Pharmacologists;
D.B.A. Narayana, R.M. Dobriyal. 29. Strategies to Identify New Compounds
and Pharmacological Activities from Traditional Herbal Medicines in Single
and Combined Usage; I. Kimura, M. Kimura. 30. Plant-Derived Agents Against
Cancer; F. Abdullaev. 31. Antidiabetic Effect of Viayasar (Pterocarpus
marsupium); R.R. Chaudhury. 32. Development of Hepatoprotective Formulation
from Plant Sources; S.S. Agrawal. 33. Kava <(Piper methysticum): From a
Pacific Island Curiosity to a Herbal Superstar; Y.N. Singh. 34.
Antiproliferative and Chemopreventive Potential of Indian Medicinal Plants,
Withania somnifera and Ocimum sanctum; S.K. Gupta, J. Prakash. 35.
Antiepileptic Drug Therapy in the New Millennium; Y.K. Gupta, J. Malhotra.
36. Neurochemical Abnormalities in the Hippocampal Formation with
Schizophrenia; E. Scarr. 37. Changes in the Dopaminergic and Serotonergic
Systems of the Prefrontal Cortex in Subjects with Schizophrenia: Evidence
from Postmortem Stuides; B. Dean. 38. The Mammalian Metabotropic GABA£Y/Y£
Receptor and Its Role; N.G. Bowery. 39. Signal-Transducing Activity of the
Natriuretic Peptide C Receptor (NPR-C) in Neuronal Tissue; G.J. Trachte.
40. Carotenoid Interactions with Cellular Isoprenoid Pathways: A Common
Mechanistic Theme for Diverse Biological Activities; W.C. Cole, K.N.
Prasad. 14. Psychotherapeutic Implications of Cooperation and
Control-Operations Among Multiple Opioid Receptors; K.K. Sharma, P.K.
Mediratta. 42. Opioid Gastrointestinal Dependence; T.F. Burks, et al. 43.
A Role for Calcium-Activated Neutral Proteinase in Myelin Protein
Degradation Associated with Optic Neuritis and Multiple Sclerosis; D.C.
Shields, N.L. Banik. 44. Myelin Galactosphingolipids as Negative Regulators
of Differentiation; R. Bansal. 45. The Need for Pharmacovigilance; S.
Olsson. 46. Pharmacovigilance and its Status in India; S.K. Gupta, U.
Singh. 47. Pharmacovigilance and Detection of Signals; A. Misra, S. Sinha.
48. Reinforcing Drug Safety and Pharmacovigilance in Graduate Medical
Curriculum; M. Thomas. 49. Treatment of Viral Pneumonia using a Combination
of Antiviral and Antiinflammatory Medications; G.A. Prince. 50.
Environmental Pollutants and Certain Therapeutic Agents Enhance the
Severity of Virus Infection: Role of Cytokines; P. Seth, et al. 51.
Inhibitory Effect of Interferon on Sexual Stages of Simian Malaria
Parasites in Rhesus Monkeys; R. Tripathi, et al. 52. Therapeutic Strategies
for Prevention of Cataract; S.K. Gupta, S. Joshi. 53. Reversal of
Cholinergic Response of Intraocular Muscles by Atropine: Drug Antagonism
Re-examined; P.N. Patil. 54. The Changing Target in the Treatment of Peptic
Ulcer: From pH to Hp; U. Klotz. 55. Nitric Oxide and Peroxynitrite in
Airway Disease; F.P. Nijkamp, G. Folkerts. 56. Therapeutic Agents for
Benign Prostatic Hyperplasia: Achieving Pharmacological Selectivity; J.P.
Hieble, A.C. Sulpizio. 57. Pharmacology Teaching, Learning and Testing at
Academic Institutions; P.N. Patil. 58. Strategies for Reduction of
Anthracycline Cardiac Toxicity; M.U.R. Naidu. 59. Cyclooxygenase
Isoenzymes: Their Selective Inhibitors; S.K. Kulkarni, et al. 60.
Contribution of the Clinical Pharmacologist to Control of Tropical
Diseases; N.A. Kshirsagar, N.J. Gogtay. 61. Glutathione S-Transferases:
Some New Functional Roles; U. Pandya, et al. 62. Catalytic Mechanism of
mGSTA4-4, An Enzyme Involved in Response to Oxidative Stress; S.P. Singh,
et al. 63. Xenobiotic Conjugates of Fatty Acids; B.S. Kaphalia, et al. 64.
Aldose Reductase Efficeintly Detoxifies Lipid Derived Aldehydes; S.K.
Srivastava, et al. 65. Identity of RLIP76 with the ATP-Dependent
Transporter for Glutathione Conjugates and Doxorubicin in Human Tissues;
S. Awasthi, et al. 66. The Protein Tyrosine Phosphatase Inhibitor Vanadyl
Sulfate Prlongs Insulin-induced Activation of Mitogen-activated Protein
Kinases ERK 1 and ERK 2 as well as Phosphatidylinositol-3-Kinase; J.-F.
Théberge, et al. Index.