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The drug discovery and development process is highly time-consuming and risky business and therefore, there is a significant quest to develop new scientific approaches to identify correlations between the nature of the drug and of its safety and efficacy in the human body (pharmacovigilance-based) so that potentially challenging drug leads could be recognized and eradicated at the earliest stages in their development, which will improve the public health and provide a safe, effective and rational use of medicines. This book is based on the importance and implication of Pharmacovigilance in the drug discovery and development process. It highlights a brief description on the role played by Pharmacovigilance at various stages of drug development, such as, risk management, clinical practice, drug regulation.